Case Western Reserve scientists have taken a huge leap toward identifying root causes of psoriasis, an inflammatory skin condition affecting 125 million people around the world. Of the roughly 50,000 proteins in the human body, researchers have zeroed in on four that appear most likely to contribute this chronic...
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Researchers develop first computer models of phospholipase A2 enzymes extracting their substrates out of the cell membrane, an early step in inflammation Phospholipase A2 (PLA2) enzymes are known to play a role in many inflammatory diseases, including asthma, arthritis and atherosclerosis. It then stands to reason that PLA2 inhibitors...
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Arthritis Research UK scientists in Edinburgh have come up with a new ‘solution’ that could reduce the risk of osteoarthritis developing in tens of thousands of people who undergo orthopaedic surgery every year – sugar. People who have surgery for joint problems are at increased risk of developing osteoarthritis...
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